install LAMP
install zabbix
sudo apt-get install zabbix-server-mysql zabbix-frontend-php
when zabbix installed with version 1.8
install zabbix 2.2.1 with zabbix-frontend-php 2.2.1-1+precise all.deb and zabbix-server-mysql 2.2.1-1+precise amd64.deb
if you already installed older version zabbix , it will remind you whether reinstall the database or not
p.s. if the requirement relate to php,need to change the php.ini, it locate to /etc/php5/apache2 and /etc/php5/cli
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